Citric Acid and Its Inorganic Salts and Alkyl and Glycol Esters as Used in Cosmetics June 9, 2011 All interested persons are provided 60 days from the above date to comment on this Scientific Literature Review and to identify additional published data that should be included or provide unpublished data which can be made public and included.
The CIR Expert Panel determined that because of structural similarities between the aliphatic esters included in this review, the available toxicity data on Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, and Acetyl Trihexyl Citrate were sufficient for evaluating the safety of Acetyl Triethylhexyl Citrate in cosmetics.
Acetyltributylcitrate. Acetyltributylcitrate is an organic compound that is used as a plasticizer. As such, it is a potential replacement of DEHP and DINP. It is a colorless liquid that is soluble in organic solvents. It is found in nail polish and other cosmetics. It is prepared by acetylation of tributylcitrate.
supply, use, toxicity, and exposure associated with acetyl tri-n-butyl citrate (ATBC). It is an update of a previous contractor report to CPSC (Versar, 2010). Literature searches for physico-chemical, toxicological, exposure, and risk information were performed in November 2017 using the CAS number and synonyms (see Appendix 1 for the full
About ACETYL TRIBUTYL CITRATE: Acetyl Tributyl Citrate is an aliphatic ester. Function(s): Fragrance Ingredient; Plasticizer; FILM FORMING; MASKING; PERFUMING; PLASTICISER
Final Report On the Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics March 27, 2012 The 2012 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V.
Unlike other pesticides for which EPA has followed a cumulative risk approach based on a common mechanism of toxicity, EPA has not made a common mechanism of toxicity finding as to acetyl tributyl citrate, triethyl citrate or any citrate esters. These esters do not appear to produce a toxic metabolite produced by other substances.
ATBC, Acetyl Tributyl Citrate, CAS: 77-90-7, is a safe, non-toxic, biodegradable and Phthalate-FREE plasticizer; mainly used in PVC, cellulose resin and synthetic rubber. Main applications are toys for children, medical products such as blood bags, food packaging materials, and cosmetics.
About ACETYL TRIETHYL CITRATE: Acetyl Triethyl Citrate is an ... 35 studies in PubMed science library may include information on the toxicity of this chemical see ...
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has been approved as it requires low toxicity and migration. Pharmaceutically used plasticizers can be categorized into hydrophobic and hydrophilic groups . The hydrophobic plasticizers include acetyl tributyl citrate (ATBC), acetyl triethyl citrate, castor oil,
2 scientific committee on toxicity, ecotoxicity and the environment (cstee) opinion on the risk assessment for acetyl tributyl citrate (atbc) plasticizer used in children's toys
Acetyl tributyl citrate | C20H34O8 | CID 6505 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...
Acetyl Tribute Citrate, also known as Acetyltributylcitrate, is a colorless liquid organic compound that is used in industry as a plasticizer in the manufacture of nail polish and other cosmetics. It is prepared by acetylation of tributylcitrate and is considered a potential replacement of DEHP and DINP.
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Structure, properties, spectra, suppliers and links for: Tributyl citrate acetate, 77-90-7.
1. Some pharmacologic and toxic properties of four citrate esters, tributyl (TBC), acetyl tributyl (ATBC), triethyl (TEC), and acetyl triethyl (ATEC) citrates, administered by the gastrointestinal route have been studied in 250 rats and 95 cats. 2. 2. The two tributyl citrates are nontoxic by the oral route in the rat and cat.
PubMed:Final report on the safety assessment of acetyl triethyl citrate, acetyl tributyl citrate, acetyl trihexyl citrate, and acetyl trioctyl citrate. PubMed:Cytocompatibility of new phthalate ester-free tissue conditioners in vitro. PubMed:Self-adhesive thin films for topical delivery of 5-aminolevulinic acid.
Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, Acetyl Trihexyl Citrate, and Acetyl Trioctyl Citrate all function as plasticizers in cosmetics. Additionally, the Trihexyl and Trioctyl forms are described as skin-conditioning agents—emollients, although there are currently no reported uses of Acetyl Trihexyl Citrate or Acetyl Trioctyl Citrate.
Acetyl Tributyl Citrate 77-90-7 Product Summary: No data available for the teratogenicity, mutagenicity, or reproductive toxicity of this product. No data available to designate the product as causing specific target organ toxicity through single or repeated exposure. No data available to designate product as an aspiration hazard. Acute Toxicity:
Safety Data Sheet Acetyl tri-n-butyl Citrate (ATBC) Page 2 of 5 MATERIAL SAFETY DATA SHEET Inhalation Move person to fresh air; if effects occur, consult a physician. Skin contact Take off contaminated clothing. Wash skin with plenty of water. Eye contact Flush eyes thoroughly with water for several minutes.
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Triethyl citrate (TEC) Acetyl triethyl citrate (ATEC), higher boiling point and lower volatility than TEC; Tributyl citrate (TBC) Acetyl tributyl citrate (ATBC), compatible with PVC and vinyl chloride copolymers; Trioctyl citrate (TOC), also used for gums and controlled release medicines; Acetyl trioctyl citrate (ATOC), also used for printing ink
Acetyl Tributyl Citrate is a plasticizer or carrier solvent permitted in the field of food additive, food contact material as well as for polymers specially for cellulosics. It is also used in s ynthesis flavoring substances and adjuvants .
No toxicity data have been established for this product. However, toxicity data for ingredients are stated below: Ingredient Name Toxicity data Acetyl tributyl citrate > 30 ml/kg oral - rat LD50; > 50 ml/kg oral - cat LD50; > 4 gm/kg interperitoneal - mouse LD50; 12600 mg/kg/14 day(s) intermittent intraperitoneal - mouse TDLo Triethyl citrate
77-90-7 - QZCLKYGREBVARF-UHFFFAOYSA-N - Acetyltributyl citrate [NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information.
Acetyl Tributyl Citrate 77-90-7 201-067-0 99.0% min. Section 5: Fire and Explosion Data Extinguishing medis: Water spray, carbon dioxide, dry chemical powder or appropriate foam.
Acetyl tributyl citrate is used as plasticizer of low toxicity, found in nail polish and other cosmetics. It's chemical formula is C20H34O8. It exists as a clear, colorless liquid.
Acetyl Tributyl Citrate(ATBC) Product name:Acetyl Tributyl Citrate(ATBC) Use:1, ATBC has very low acute toxicity, mice by oral test up to 30g/kg.Experimental study on subacute toxicity of recent (90 days) show that, even in the ATBC feeding concentration up to 5% of cases, noobvious damage to liver.
Toxicity Profile for Acetyl tributyl citrate (2002) A two-generation study in rats treated orally found evidence of reproductive toxicity at maternally toxic doses. A limited oral long-term study detected no evidence of carcinogenic potential in rats. Acetyl tributyl citrate was not mutagenic in the Ames bacterial assay and in general did not induce...